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Tuesday, May 12, 2020 | History

3 edition of Evaluation of the role of the sympathetic nervous system in primary hypertension found in the catalog.

Evaluation of the role of the sympathetic nervous system in primary hypertension

Evaluation of the role of the sympathetic nervous system in primary hypertension

through measurement of plasma catecholamines during rest and exercise

  • 23 Want to read
  • 32 Currently reading

Published .
Written in English

    Subjects:
  • Hypertension,
  • Catecholamines,
  • Exercise -- Physiological aspects,
  • Sympathetic nervous system

  • Edition Notes

    Statementby James Allen Knight
    The Physical Object
    FormatMicroform
    Paginationviii, 80 leaves
    Number of Pages80
    ID Numbers
    Open LibraryOL14413354M

    The sympathetic dysfunction depends on a variety of reflex and nonreflex mechanisms and participates at development and progression of the essential hypertensive state. This has been shown to be the case for borderline hypertension, for moderate and severe high blood pressure, and for resistant hypertension as by: The role of the sympathetic nervous system (SNS) in the pathogenesis of hypertension (HT) has been remarkably changed over the past 50 years. Indeed, until a few decades ago it was believed that sympathetic neural influences were almost univocally involved in the short-term blood pressure (BP) control, with limited or even no impact at all on long-term BP regulation and development of high by:

    We examined the role of the sympathetic nervous system in the antihypertensive effect of long-term (4-week) administration of cicletanine (50 mg/ g in diet) in young (6 week-old) spontaneously. Purpose of review A number of cardiovascular disease have been shown to be characterized by a marked increase in sympathetic drive to the heart and peripheral circulation. This is the case for essential hypertension, congestive heart failure, obesity, metabolic syndrome and chronic renal review focuses on the most recent findings documenting the role of sympathetic neural .

      The sympathetic nervous system (SNS) is one of the two divisions of the autonomic nervous system (ANS), the other being the parasympathetic nervous system (PNS), These systems largely work unconsciously in opposite ways to regulate many functions and parts of the body. Colloquially, the SNS governs the "fight or flight" response while the PNS controls the "rest and Author: Mark N. Alshak, Joe M Das. Primary Hypertension Between 21% and 36% of the adult population in the United States • Increased sympathetic nervous system activity related to Evaluation, and Treatment of High Blood Press ure. (). JAMA, (19), – Table File Size: KB.


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Evaluation of the role of the sympathetic nervous system in primary hypertension Download PDF EPUB FB2

There is considerable evidence that sympathetic nervous system plays an impor-tant role in the pathogenesis of several cardiovascular diseases including hypertension. Most of the important evidence is based on the microneurographic method of intraneural record-ings of sympathetic nerve activity and radiotracer techniques for the study of the norepi-nephrine : C.L.

Kaul, P. Ramarao. A number of cardiovascular disease have been shown to be characterized by a marked increase in sympathetic drive to the heart and the peripheral circulation.

This is the case for essential hypertension, congestive heart failure, cardiac arrhythmias, obesity, metabolic syndrome, obstructive sleep apnea, and chronic renal disease. This review focuses on the most recent findings documenting Cited by: The sympathetic nervous system (SNS) plays an important role in the regulation of cardiac performance and peripheral circulation.

Changes in SNS activity measured as catecholamines in plasma or organ spillover have been implicated in the pathogenesis of by: SUMMARY: The sympathetic nervous system represents a major pathophysiological hallmark of both hypertension and renal failure and is an important target for the therapeutic intervention Cited by: The sympathetic nervous system plays an important role in the regulation of arterial pressure, and increased sympathetic nervous system activity has been implicated as a primary precursor of hypertension in both humans and animal models of the by: Abstract.

Despite early demonstrations that sympathetic activation elevates blood pressure and early clinical inklings that human hypertension may have a psychosomatic component, the pivotal role of the nervous system in human hypertension is only recently being by: 8. The sympathetic nervous system is an important regulatory mechanism of both metabolic and cardiovascular function, and altered sympathetic activity may play a role in the etiology and/or.

The sympathetic nervous system (SNS) is part of the ANS which is importa nt for the regulatory mechan isms of blood pressure, electrolyte balance, and maintenanceAuthor: Narsingh Verma. Along with raised vasomotor tone and increased cardiac output, the chronic activation of the sympathetic nervous system in hypertension has a Cited by: Hypertension and Sympathetic Nervous System Activity David A.

Calhoun Suzanne Oparil Vascular Biology and Hypertension Program University of Alabama Birmingham Birmingham, Alabama Vascular Biology and Hypertension Program University of Alabama Birmingham Birmingham, Alabama Sympathetic nervous system activity is increased in both the developmental and chronic stages of primary Cited by: 7.

primary hypertension is a vicious syndrome involving abnormal adiposity, overactivation of the adrenergic system, metabolic abnormalities, and activation of the immune Size: KB. ic function. Recent studies have used sophisticated and sensitive techniques to evaluate sympathetic activity in humans, e.g.

the norepinephrine spillover method and the microneurographic quantification of sympathetic nerve traffic, allowing documentation of the participation of adrenergic mechanisms in the early and late phases of the hypertensive process.

Evidence has been also provided that. In primary human hypertension, analysis of regional sympathetic nervous system function has demonstrated activation of the sympathetic nervous outflows to the heart, the kidneys, and skeletal muscle vasculature, particularly in younger patients.

4,5 This sympathetic activation no doubt contributes to blood pressure elevation, but has been Cited by:   Nearly one-third of the world’s population has hypertension.

The human and societal impact of hypertension is enormous. Primary hypertension accounts for 95 % of cases of hypertension in adults.

The pathogenesis of primary hypertension is complex. The kidney and the sympathetic nervous system play important roles in the development and maintenance of by: 9. Evaluation of the role of the sympathetic nervous system in primary hypertension through measurement of plasma catecholamines during rest and exercise Author: James Allen Knight.

A number of articles have dealt with the importance and mechanisms of the sympathetic nervous system alterations in experimental animal models of hypertension. This review addresses the role of the sympathetic nervous system in the pathophysiology and therapy of human hypertension.

We first discuss the strengths and limitations of various techniques for assessing the sympathetic nervous system Cited by:   Never the less, the sympathetic nervous system appears to play an important role in the pathogenesis, sequelae and therapy of PH.

The sympathetic nervous system: the muse of primary hypertension Cited by: Johansson M, Herlitz H, Jensen G, et al.: Increased cardiovascular mortality in hypertensive patiens with renal artery on to sympathetic activation, renal function and treatment regimens.J Hypertens–A study showing elevated cardiovascular mortality in patients with hypertension and renovascular disease compared with the normal population of by: 6.

Objective To determine if the contribution of the sympathetic nervous system to blood pressure could be evidenced by low-frequency oscillations of systolic blood pressure (LF SBP), reflecting vascular sympathetic modulation, or by the decrease in blood pressure after autonomic blockade.

Design We studied multiple system atrophy (MSA) patients, in whom supine hypertension is maintained by. The sympathetic nervous system plays an important role in the pathogenesis of primary hypertension and in certain secondary forms of hypertension.

Although hypertension is a disease of multifactorial etiology, the pathophysiological role of neuroadrenergic factors is Cited by:. Amongst other factors, unfavorable genetic substrate, activated sympathetic nervous system (SNS) and renin-angiotensin system, excess sodium intake and disturbances between vasoconstrictors and vasodilators have been implicated in the pathophysiology of HTN.

Although the role of the above factors in the pathogenesis of essential HTN is well established, their involvement in Cited by: Arterial Baroreflex Control of Renal Sympathetic Nerve Activity and the Renal Body Fluid Feedback Mechanism— A Revisionist View.

A major hypothesisfor the development of hypertension is that abnormal renal excretory function is critical for the initiation, development, and maintenance of primary hypertension.

1 The renal body fluid feedback mechanism couples the long-term regulation of Cited by:   The Role of the Sympathetic Nervous System in Essential Hypertension in Man. Reginald H. Smithwick. Angiology 2: 4 The Role of the Sympathetic Nervous System in Essential Hypertension in Man Show all authors.

Reginald H. by: 4.